Linked Life Data

18633774

Source:http://linkedlifedata.com/resource/pubmed/id/18633774

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-7-17
pubmed:abstractText
Self-related processing, reflecting the evaluation of environmental signals with regard to personal relevance, is fundamental for decision-making and subsequent behavioral responses. While self-related processing has already been investigated in several domains, one important domain, the sexual domain, has been spared so far. Recent imaging studies suggest that self-related processing in different domains involves common regions in medial orbitofrontal and prefrontal cortex, the so-called ventral cortical midline structures (CMS). However, the same regions have also been implicated in sexual arousal, especially with regard to emotional processing in sexual arousal. Therefore it remains unclear whether this involvement of ventral cortical midline regions reflects emotional processing in sexual arousal or associated self-relatedness. We here report data from a parametric event-related fMRI study that investigated the neural correlates of self-related processing in sexual arousal, using erotic pictures from the International Affective Picture System. It was found that self-related activity associated with sexual arousal showed neural activity in ventral CMS regions such as the venteromedial prefrontal cortex (VMPFC) and the perigenual anterior cingulate cortex (PACC), while self-related activity not associated with sexual arousal showed neural activity in the dorsomedial prefrontal cortex (DMPFC). Our study indicates that self-relatedness may be considered a crucial component in sexual arousal that is mediated by neural activity in ventral cortical midline structures.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1747-0927
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
41-51
pubmed:dateRevised
2009-12-11
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Self-related processing in the sexual domain: a parametric event-related fMRI study reveals neural activity in ventral cortical midline structures.
pubmed:affiliation
University of Dusseldorf at the Research Centre Juelich, Dusseldorf, Germany.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't