Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-7-17
pubmed:abstractText
Using reverse transcriptase-polymerase chain reaction (RT-PCR), REG 1A mRNA expression was investigated in 235 primary gastric carcinoma samples. And the relation between these results with the clinicopathologic parameters of primary gastric carcinoma was discussed in experiment. The positive REG 1A mRNA is 78% (183/235) of primary gastric carcinoma which revealed by RT-PCR analysis. Moreover, patients with REG 1A-positive differentiated adenocarcinoma were found to have a significantly poorer prognosis compared with REG 1A-negative tumor patients. REG IA mRNA is closely linked to the infiltrative growth pattern and with signet ring cell carcinoma and poorly differentitated adencarcinoma. And the incidence of venous invasion of REG 1A-positive tumors was significantly higher than that of REG 1A-negative tumors. So the results of the experiment demonstrate that the expression of the REG 1A gene is closely related to the infiltrating property of primary gastric carcinoma, and may be as a prognostic indicator of differentiated adenocarcinoma of the stomach in clinic diagnosis.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1673-520X
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
174-82
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
[The relation between reg 1A mRNA expression and the clinicopathologic parameters in the patients with primary gastric carcinoma].
pubmed:affiliation
College of Medicine, Zhejiang University, Hangzhou.
pubmed:publicationType
Journal Article, English Abstract