To investigate the Notch 3 mutation spectrum in Arab patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy CADASIL, which is an inherited cerebrovascular disease characterized by recurrent subcortical ischemic stroke starting in the third or fourth decade.
Department of Neurosciences, King Faisal Specialist Hospital & Research Centre, PO Box 3354, MBC 76, Riyadh 11211, Kingdom of Saudi Arabia. boholega@kshrc.edu.sa