| pubmed-article:18625554 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18625554 | lifeskim:mentions | umls-concept:C1955880 | lld:lifeskim |
| pubmed-article:18625554 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:18625554 | lifeskim:mentions | umls-concept:C1880355 | lld:lifeskim |
| pubmed-article:18625554 | pubmed:issue | 15 | lld:pubmed |
| pubmed-article:18625554 | pubmed:dateCreated | 2008-7-29 | lld:pubmed |
| pubmed-article:18625554 | pubmed:abstractText | Novel non-nucleoside inhibitors of HIV-RT that contain pyridazinone isosteres were prepared, and a series of triazolinones were found to be potent inhibitors of HIV replication. These compounds were active against several NNRTI-resistant virus strains. Pharmacokinetic studies indicated that inhibitor 7e has good bioavailability in rats. Several fragments of inhibitor 7c were prepared, and the binding of these compounds to HIV-RT was analyzed by surface plasmon resonance spectroscopy. | lld:pubmed |
| pubmed-article:18625554 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18625554 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18625554 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18625554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18625554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18625554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18625554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18625554 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18625554 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:18625554 | pubmed:issn | 1464-3405 | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:YuLiL | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:SmithMarkM | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:MartinMichael... | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:WuJeffreyJ | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:BriggsAndrewA | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:GiannettiAnth... | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:KlumppKlausK | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:DunnJames PJP | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:SweeneyZachar... | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:HangJulie QJQ | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:SaitoY... | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:ElworthyTodd... | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:SwallowSteven... | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:HeilekGabriel... | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:AcharyaSahaja... | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:FretlandJenni... | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:KaiserAnn CAC | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:SuhJudy MJM | lld:pubmed |
| pubmed-article:18625554 | pubmed:author | pubmed-author:ZhouAmy SAS | lld:pubmed |
| pubmed-article:18625554 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18625554 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:18625554 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:18625554 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18625554 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18625554 | pubmed:pagination | 4348-51 | lld:pubmed |
| pubmed-article:18625554 | pubmed:meshHeading | pubmed-meshheading:18625554... | lld:pubmed |
| pubmed-article:18625554 | pubmed:meshHeading | pubmed-meshheading:18625554... | lld:pubmed |
| pubmed-article:18625554 | pubmed:meshHeading | pubmed-meshheading:18625554... | lld:pubmed |
| pubmed-article:18625554 | pubmed:meshHeading | pubmed-meshheading:18625554... | lld:pubmed |
| pubmed-article:18625554 | pubmed:meshHeading | pubmed-meshheading:18625554... | lld:pubmed |
| pubmed-article:18625554 | pubmed:meshHeading | pubmed-meshheading:18625554... | lld:pubmed |
| pubmed-article:18625554 | pubmed:meshHeading | pubmed-meshheading:18625554... | lld:pubmed |
| pubmed-article:18625554 | pubmed:meshHeading | pubmed-meshheading:18625554... | lld:pubmed |
| pubmed-article:18625554 | pubmed:meshHeading | pubmed-meshheading:18625554... | lld:pubmed |
| pubmed-article:18625554 | pubmed:meshHeading | pubmed-meshheading:18625554... | lld:pubmed |
| pubmed-article:18625554 | pubmed:meshHeading | pubmed-meshheading:18625554... | lld:pubmed |
| pubmed-article:18625554 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18625554 | pubmed:articleTitle | Discovery of triazolinone non-nucleoside inhibitors of HIV reverse transcriptase. | lld:pubmed |
| pubmed-article:18625554 | pubmed:affiliation | Roche Palo Alto LLC, 3431 Hillview Avenue, Palo Alto, CA 94304, USA. zachary.sweeney@roche.com | lld:pubmed |
| pubmed-article:18625554 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:18625554 | lld:chembl |
