Linked Life Data

18625311

Source:http://linkedlifedata.com/resource/pubmed/id/18625311

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2008-10-22
pubmed:abstractText
Human embryonic stem cells possess the unique ability to differentiate into any adult cell type. Recent advances in the understanding of stem cell biology make new applications possible for stem cell based technology. Of note, it is now possible to reprogram terminally differentiated human somatic cells into pluripotent cells that are functionally equivalent to embryonic stem cells. These induced pluripotent cells may become the substrate for future disease models and cell-based therapies. In addition, novel techniques for genetic manipulation have increased the ease with which genes can be modified into stem cells. In this review, we describe these novel technologies as well as developments in the understanding of basic biology of stem cell pluripotency and differentiation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0959-437X
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
324-9
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Human embryonic stem cells: emerging technologies and practical applications.
pubmed:affiliation
Stowers Medical Institute, Harvard Stem Cell Institute, Center for Regenerative Medicine, Cardiovascular Research Center, Massachusetts General Hospital, 185 Cambridge Street, CPZN-4234, Boston, MA 02114, United States.
pubmed:publicationType
Journal Article, Review