Source:http://linkedlifedata.com/resource/pubmed/id/18624684
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2008-7-15
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pubmed:abstractText |
After the tragic events in the early 1960s, thalidomide has re-emerged as therapeutic for multiple myeloma (MM). It was first approved for the treatment of erythema nodosum leprosum, and is now under evaluation for hematologic and non-hematologic disorders. Its complex mechanism of action is not fully understood; however extensive preclinical studies in MM have revealed its antiangiogenic and immunomodulatory properties.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1742-5255
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
973-85
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pubmed:dateRevised |
2009-11-16
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pubmed:meshHeading |
pubmed-meshheading:18624684-Angiogenesis Inhibitors,
pubmed-meshheading:18624684-Animals,
pubmed-meshheading:18624684-Clinical Trials as Topic,
pubmed-meshheading:18624684-Drug Interactions,
pubmed-meshheading:18624684-Female,
pubmed-meshheading:18624684-Humans,
pubmed-meshheading:18624684-Immunosuppressive Agents,
pubmed-meshheading:18624684-Male,
pubmed-meshheading:18624684-Multiple Myeloma,
pubmed-meshheading:18624684-Pregnancy,
pubmed-meshheading:18624684-Thalidomide
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pubmed:year |
2008
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pubmed:articleTitle |
Thalidomide in multiple myeloma--clinical trials and aspects of drug metabolism and toxicity.
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pubmed:affiliation |
Dana-Farber Cancer Institute, LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Department of Medical Oncology, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA. Iris_Breitkreutz@dfci.harvard.edu
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pubmed:publicationType |
Journal Article,
Review
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