Linked Life Data

18623194

Source:http://linkedlifedata.com/resource/pubmed/id/18623194

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-3-2
pubmed:abstractText
The high-pressure effects on chlorpropamide (C10H13ClN2O3S) form-A have been studied by 1H NMR spectroscopy at high pressures up to 800 MPa in the temperature range 90-300 K. A study of the NMR second moment and spin-lattice relaxation time has been completed by a calculation of the steric hindrances for molecular reorientations and simulations of the second moment of the NMR line by the Monte-Carlo method, which enabled a precise description of molecular dynamics in the compound studied. Reorientations of the methyl group, oscillations and reorientations of the chlorophenyl ring and reorientations of the propyl group have been revealed and respective activation parameters extracted. No phase transformation of the compound form-A has been detected.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1520-6017
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
98
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1426-37
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
NMR search for polymorphic phase transformations in chlorpropamide form-A at high pressures.
pubmed:affiliation
Faculty of Physics, A. Mickiewicz University, Umultowska 85, 61-614 Pozna?, Poland. jwasicki@amu.edu.pl
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't