Linked Life Data

18623072

Source:http://linkedlifedata.com/resource/pubmed/id/18623072

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2008-7-17
pubmed:abstractText
The outline of a universal cell-free translation system capable of site-specific insertion of any types of labeled amino acids is presented. The system could be an invaluable tool for NMR spectroscopy by making the exclusive and exact labeling of the segments of interest possible. Although the development of such a system requires considerable efforts and can not be expected to be available in the next few years, we argue that recent findings concerning the translation apparatus provide clues for overcoming the major difficulties that might arise. We propose a genetic code and a reactor expected to fulfill the specific requirements. Importantly, incomplete systems could also be useful to study selected functional aspects of a number of proteins, examples of which are also given.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1521-1878
pubmed:author
pubmed:copyrightInfo
(c) 2008 Wiley Periodicals, Inc.
pubmed:issnType
Electronic
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
772-80
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
A redesigned genetic code for selective labeling in protein NMR.
pubmed:affiliation
Institute of Chemistry, Eötvös Loránd University, Budapest, Hungary. szpari@chem.elte.hu
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural