pubmed-article:1862284 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1862284 | lifeskim:mentions | umls-concept:C0020971 | lld:lifeskim |
pubmed-article:1862284 | lifeskim:mentions | umls-concept:C0012634 | lld:lifeskim |
pubmed-article:1862284 | lifeskim:mentions | umls-concept:C0011750 | lld:lifeskim |
pubmed-article:1862284 | lifeskim:mentions | umls-concept:C0018483 | lld:lifeskim |
pubmed-article:1862284 | pubmed:dateCreated | 1991-9-5 | lld:pubmed |
pubmed-article:1862284 | pubmed:abstractText | Haemophilus influenzae is one of the leading causes of severe bacterial infection in children of developing regions, causing 30% of the cases of culture-positive pneumonia and 20%-60% of the cases of bacterial meningitis. In infants and children, the majority of isolates from cerebrospinal fluid and blood and 16%-38% of pulmonary isolates are H. influenzae type b. The availability of several new polysaccharide-protein conjugate vaccines for the prevention of invasive disease due to H. influenzae type b prompts this review of the epidemiology of H. influenzae disease in the developing world and of the characteristics of current H. influenzae type b vaccines. To develop a strategy for use of H. influenzae type b vaccines in developing countries, the following data are needed: the age-specific attack rates of H. influenzae type b disease and the immunogenicity and efficacy of these vaccines in young infants in developing countries. Should H. influenzae type b vaccines prove to be inadequate for the prevention of H. influenzae pneumonia, the use of non-type b H. influenzae vaccines may be necessary. | lld:pubmed |
pubmed-article:1862284 | pubmed:language | eng | lld:pubmed |
pubmed-article:1862284 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1862284 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1862284 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1862284 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1862284 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1862284 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1862284 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1862284 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1862284 | pubmed:issn | 0162-0886 | lld:pubmed |
pubmed-article:1862284 | pubmed:author | pubmed-author:SteinhoffM... | lld:pubmed |
pubmed-article:1862284 | pubmed:author | pubmed-author:WardJJ | lld:pubmed |
pubmed-article:1862284 | pubmed:author | pubmed-author:FunkhouserAA | lld:pubmed |
pubmed-article:1862284 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1862284 | pubmed:volume | 13 Suppl 6 | lld:pubmed |
pubmed-article:1862284 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1862284 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1862284 | pubmed:pagination | S542-54 | lld:pubmed |
pubmed-article:1862284 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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pubmed-article:1862284 | pubmed:articleTitle | Haemophilus influenzae disease and immunization in developing countries. | lld:pubmed |
pubmed-article:1862284 | pubmed:affiliation | Department of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, Maryland. | lld:pubmed |
pubmed-article:1862284 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1862284 | pubmed:publicationType | Review | lld:pubmed |
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