18611978

Source:http://linkedlifedata.com/resource/pubmed/id/18611978

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0014939, umls-concept:C0036667, umls-concept:C0043210, umls-concept:C0232970, umls-concept:C0312418, umls-concept:C0911014, umls-concept:C1515075, umls-concept:C2349975
pubmed:issue	10
pubmed:dateCreated	2008-10-9
pubmed:abstractText	Sex-steroid hormones amplify pulsatile GH secretion by unknown mechanisms. Ghrelin is the most potent natural GH secretagogue discovered to date. A plausible unifying postulate is that estradiol (E(2)) enhances hypothalamo-pituitary sensitivity to ghrelin (a physiological effect). The hypothesis is relevant to understanding the basis of hyposomatotropism in aging and other relatively hypogonadal states.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/R01 AG19695, http://linkedlifedata.com/resource/pubmed/grant/R01 AG29362, http://linkedlifedata.com/resource/pubmed/grant/UL 1 RR024150
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0375362
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Estradiol, http://linkedlifedata.com/resource/pubmed/chemical/Follicle Stimulating Hormone, http://linkedlifedata.com/resource/pubmed/chemical/Ghrelin, http://linkedlifedata.com/resource/pubmed/chemical/Human Growth Hormone, http://linkedlifedata.com/resource/pubmed/chemical/Insulin-Like Growth Factor Binding..., http://linkedlifedata.com/resource/pubmed/chemical/Insulin-Like Growth Factor I, http://linkedlifedata.com/resource/pubmed/chemical/Luteinizing Hormone
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	0021-972X
pubmed:author	pubmed-author:BowersCyril YCY, pubmed-author:CosmaMihaelaM, pubmed-author:KokPetraP, pubmed-author:MielkeKristi LKL, pubmed-author:MilesJohn MJM, pubmed-author:PauloRemberto CRC, pubmed-author:VeldhuisJohannes DJD
pubmed:issnType	Print
pubmed:volume	93
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	4020-6
pubmed:dateRevised	2010-9-21
pubmed:meshHeading	pubmed-meshheading:18611978-Circadian Rhythm, pubmed-meshheading:18611978-Drug Resistance, pubmed-meshheading:18611978-Drug Synergism, pubmed-meshheading:18611978-Estradiol, pubmed-meshheading:18611978-Estrogen Replacement Therapy, pubmed-meshheading:18611978-Female, pubmed-meshheading:18611978-Follicle Stimulating Hormone, pubmed-meshheading:18611978-Ghrelin, pubmed-meshheading:18611978-Human Growth Hormone, pubmed-meshheading:18611978-Humans, pubmed-meshheading:18611978-Hypothalamo-Hypophyseal System, pubmed-meshheading:18611978-Insulin-Like Growth Factor Binding Proteins, pubmed-meshheading:18611978-Insulin-Like Growth Factor I, pubmed-meshheading:18611978-Luteinizing Hormone, pubmed-meshheading:18611978-Middle Aged, pubmed-meshheading:18611978-Organ Specificity, pubmed-meshheading:18611978-Postmenopause
pubmed:year	2008
pubmed:articleTitle	Estrogen supplementation selectively enhances hypothalamo-pituitary sensitivity to ghrelin in postmenopausal women.
pubmed:affiliation	Department of Internal Medicine, Mayo School of Graduate Medical Education, Clinical Translational Science Center, Mayo Clinic, Rochester, Minnesota 55905, USA.
pubmed:publicationType	Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural