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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2008-10-22
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pubmed:abstractText |
Severe acute pancreatitis (SAP) frequently progresses to pancreatitis-associated multiorgan failure (MOF) with high mortality. Decreased plasma ADAMTS13 activity (ADAMTS13:AC) results in the accumulation of unusually large von Willebrand factor multimers (UL-VWFM) and the formation of platelet thrombi, ultimately leading to MOF. The purpose of the study was to investigate the potential role of ADAMTS13:AC in the severity of SAP.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1502-7708
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pubmed:author |
pubmed-author:FujimotoMasaoM,
pubmed-author:FujimuraYoshihiroY,
pubmed-author:FukuiHiroshiH,
pubmed-author:HataMichiakiM,
pubmed-author:IshikawaMasatoshiM,
pubmed-author:IshizashiHiromichiH,
pubmed-author:KatoSeijiS,
pubmed-author:MatsumotoMasanoriM,
pubmed-author:MatsuyamaTomomiT,
pubmed-author:MitoroAkiraA,
pubmed-author:MoriokaChieC,
pubmed-author:NishinoKenjiK,
pubmed-author:OkuchiKazuoK,
pubmed-author:SawaiMasayoshiM,
pubmed-author:TsujimotoTatsuhiroT,
pubmed-author:UemuraMasahitoM,
pubmed-author:UrizonoYasuyukiY,
pubmed-author:YamaoJunichiJ,
pubmed-author:YoshidaMotoyukiM,
pubmed-author:YoshijiHitoshiH
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pubmed:issnType |
Electronic
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1387-96
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pubmed:meshHeading |
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pubmed:year |
2008
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pubmed:articleTitle |
Plasma ADAMTS13 activity parallels the APACHE II score, reflecting an early prognostic indicator for patients with severe acute pancreatitis.
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pubmed:affiliation |
Third Department of Internal Medicine, Nara Medical University, Kashihara, Nara, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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