Linked Life Data

18607415

Source:http://linkedlifedata.com/resource/pubmed/id/18607415

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14
pubmed:dateCreated
2008-7-8
pubmed:abstractText
Zero-Mode Waveguides were first introduced for Fluorescence Correlation Spectroscopy at micromolar dye concentrations. We show that combining zero-mode waveguides with fluorescence correlation spectroscopy in a continuous flow mixer avoids the compression of the FCS signal due to fluid transport at channel velocities up to approximately 17 mm/s. We derive an analytic scaling relationship [equation: see text] converting this flow velocity insensitivity to improved kinetic rate certainty in time-resolved mixing experiments. Thus zero-mode waveguides make FCS suitable for direct kinetics measurements in rapid continuous flow.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1094-4087
pubmed:author
pubmed:issnType
Electronic
pubmed:day
7
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
10077-90
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Single molecule correlation spectroscopy in continuous flow mixers with zero-mode waveguides.
pubmed:affiliation
Department of Physics, Princeton University, Princeton, NJ 08544, USA. dliao@princeton.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.