Source:http://linkedlifedata.com/resource/pubmed/id/18606032
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2008-7-8
|
| pubmed:abstractText |
The effect of the Video-Feedback Intervention to Promote Positive Parenting and Sensitive Discipline (VIPP-SD) on daily cortisol production was tested in a randomized controlled trial with 130 families with 1- to 3-year-old children screened for their relatively high levels of externalizing behavior. Six 1.5-hr intervention sessions focusing on maternal sensitivity and discipline were conducted with individual families at their homes. Children in the intervention group showed lower cortisol levels, with a moderating role of the dopamine receptor D4 (DRD4) VNTR exon III polymorphism. The VIPP-SD program proved to be effective in decreasing daily cortisol production in children with the DRD4 7-repeat allele, but not in children without the DRD4 7-repeat allele. Our findings indicate that children are differentially susceptible to intervention effects dependent on the presence of the 7-repeat DRD4 allele.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1469-2198
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
20
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
805-20
|
| pubmed:meshHeading |
pubmed-meshheading:18606032-Alleles,
pubmed-meshheading:18606032-Arousal,
pubmed-meshheading:18606032-Behavior Therapy,
pubmed-meshheading:18606032-Child, Preschool,
pubmed-meshheading:18606032-Child Behavior Disorders,
pubmed-meshheading:18606032-Education,
pubmed-meshheading:18606032-Exons,
pubmed-meshheading:18606032-Genetic Predisposition to Disease,
pubmed-meshheading:18606032-Humans,
pubmed-meshheading:18606032-Hydrocortisone,
pubmed-meshheading:18606032-Infant,
pubmed-meshheading:18606032-Internal-External Control,
pubmed-meshheading:18606032-Minisatellite Repeats,
pubmed-meshheading:18606032-Mother-Child Relations,
pubmed-meshheading:18606032-Object Attachment,
pubmed-meshheading:18606032-Polymorphism, Genetic,
pubmed-meshheading:18606032-Receptors, Dopamine D4,
pubmed-meshheading:18606032-Temperament,
pubmed-meshheading:18606032-Video Recording
|
| pubmed:year |
2008
|
| pubmed:articleTitle |
Effects of an attachment-based intervention on daily cortisol moderated by dopamine receptor D4: a randomized control trial on 1- to 3-year-olds screened for externalizing behavior.
|
| pubmed:affiliation |
Centre for Child and Family Studies, Leiden University, The Netherlands. bakermans@fsw.leidenuniv.nl
|
| pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|