Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2008-10-15
pubmed:abstractText
The aims of this study were to establish the nutritional status of patients during hematopoietic SCT (HSCT) and to determine if body mass index (BMI) is a valid indicator of nutritional status in this population when compared with nitrogen balance (NB). In total, 50 patients were enrolled (mean age: 25.7+/-9.0 years). Patients (14%) were underweight (BMI<18.5 kg/m(2)), 58% in a normal BMI (between 18.5 and 24.9 kg/m(2)) and 28% were overweight or obese (BMI >or= 25 kg/m(2)). NB dropped after transplantation and increased from days +5 to +20 after transplantation (P=0.006). There was a significant negative relationship between patients' BMI and time to engraftment (r=-0.45, P=0.001). Engraftment of underweight patients was 3.0 days (P=0.002) and 4.0 days (P<0.001) later than in normal and overweight or obese patients, respectively. There was no significant correlation between NB before transplantation and time to engraftment (r=-0.22, P=0.16). The results of this study demonstrate that patients undergoing HSCT may have suboptimal nutritional status and that pre-HSCT-BMI rather than NB may have a greater correlation in HSCT patients with the time of engraftment. Therefore, it may be useful to consider patient's BMI before transplantation for earlier engraftment time.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0268-3369
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
469-73
pubmed:meshHeading
pubmed-meshheading:18604243-Adult, pubmed-meshheading:18604243-Body Mass Index, pubmed-meshheading:18604243-Cross-Sectional Studies, pubmed-meshheading:18604243-Energy Intake, pubmed-meshheading:18604243-Female, pubmed-meshheading:18604243-Graft vs Host Disease, pubmed-meshheading:18604243-Hematopoietic Stem Cell Transplantation, pubmed-meshheading:18604243-Humans, pubmed-meshheading:18604243-Male, pubmed-meshheading:18604243-Mucositis, pubmed-meshheading:18604243-Nitrogen, pubmed-meshheading:18604243-Nutritional Status, pubmed-meshheading:18604243-Obesity, pubmed-meshheading:18604243-Overweight, pubmed-meshheading:18604243-Peripheral Blood Stem Cell Transplantation, pubmed-meshheading:18604243-Reproducibility of Results, pubmed-meshheading:18604243-Thinness, pubmed-meshheading:18604243-Transplantation, Autologous, pubmed-meshheading:18604243-Transplantation, Homologous
pubmed:year
2008
pubmed:articleTitle
Evaluation of nutritional status in patients undergoing hematopoietic SCT.
pubmed:affiliation
Faculty of Pharmacy, Department of Clinical Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't