Source:http://linkedlifedata.com/resource/pubmed/id/18603779
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2008-7-23
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pubmed:abstractText |
We determined the effects of yolk water-soluble protein (YSP) on bone resorption. YSP potently suppressed osteoclastogenesis from bone marrow-derived precursor cells driven by tumor necrosis factor-alpha (TNF-alpha). YSP (200 microg/ml) abolished the formation of tartarate-resistant acid phosphatase (TRAP)-positive osteoclasts. Furthermore, TNF-alpha induced TRAP activity was greatly inhibited by YSP (100 microg/ml) treatment. Our results suggest that YSP has therapeutic potential for bone-erosive diseases.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1347-6947
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1929-31
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pubmed:meshHeading |
pubmed-meshheading:18603779-Acid Phosphatase,
pubmed-meshheading:18603779-Animals,
pubmed-meshheading:18603779-Bone Resorption,
pubmed-meshheading:18603779-Cell Differentiation,
pubmed-meshheading:18603779-Cells, Cultured,
pubmed-meshheading:18603779-Egg Proteins,
pubmed-meshheading:18603779-Isoenzymes,
pubmed-meshheading:18603779-Male,
pubmed-meshheading:18603779-Mice,
pubmed-meshheading:18603779-Osteoclasts,
pubmed-meshheading:18603779-Osteoporosis
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pubmed:year |
2008
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pubmed:articleTitle |
Inhibitory effects of egg yolk soluble protein on bone resorption.
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pubmed:affiliation |
Department of Food and Biotechnology, Hanseo University, Seosan, Chungnam, South Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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