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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-4-27
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pubmed:abstractText |
Prostate-specific antigen (PSA) is a protein specifically expressed in prostate cells. Therefore, the expression levels of PSA in the blood are an important indicator when diagnosing prostate cancer. Defining the mechanism of PSA expression in prostate cells will be helpful for interpreting the expression of this protein during prostate cancer progression. Reports show that a membrane protein, claudin-7 (CLDN-7), is involved in the expression of PSA. However, the mechanism by which CLDN-7 regulates PSA expression is not clear. Here we identify proteins that interact with CLDN-7 and determine whether such proteins can regulate PSA expression in a pattern similar to that of CLDN-7.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1527-9995
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pubmed:author |
pubmed-author:BerensonJames RJR,
pubmed-author:CampbellRichard ARA,
pubmed-author:ChenIrvin S YIS,
pubmed-author:ChiuRobertR,
pubmed-author:KamataMasakazuM,
pubmed-author:KrethJensJ,
pubmed-author:PangShenS,
pubmed-author:ShiWenyuanW,
pubmed-author:WangQiuweiQ,
pubmed-author:XieYimingY,
pubmed-author:YanXinminX,
pubmed-author:ZhengJun-YingJY
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pubmed:issnType |
Electronic
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1119-25
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pubmed:meshHeading |
pubmed-meshheading:18602143-Cell Adhesion Molecules,
pubmed-meshheading:18602143-Cell Line, Tumor,
pubmed-meshheading:18602143-Disease Progression,
pubmed-meshheading:18602143-Gene Expression Profiling,
pubmed-meshheading:18602143-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18602143-Humans,
pubmed-meshheading:18602143-Male,
pubmed-meshheading:18602143-Membrane Proteins,
pubmed-meshheading:18602143-Prostate-Specific Antigen,
pubmed-meshheading:18602143-Prostatic Neoplasms,
pubmed-meshheading:18602143-RNA, Messenger,
pubmed-meshheading:18602143-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18602143-Sensitivity and Specificity,
pubmed-meshheading:18602143-Structure-Activity Relationship,
pubmed-meshheading:18602143-Transfection,
pubmed-meshheading:18602143-Tumor Markers, Biological,
pubmed-meshheading:18602143-Up-Regulation
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pubmed:year |
2009
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pubmed:articleTitle |
Regulation of prostate-specific antigen expression by the junctional adhesion molecule A.
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pubmed:affiliation |
University of California-Los Angeles Dental Research Institute and University of California-Los Angeles School of Dentistry, Los Angeles, California 90095-1668 , USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.
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