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rdf:type |
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|
lifeskim:mentions |
umls-concept:C0005456,
umls-concept:C0011847,
umls-concept:C0011881,
umls-concept:C0017398,
umls-concept:C0022646,
umls-concept:C0030705,
umls-concept:C0033413,
umls-concept:C0332281,
umls-concept:C0332307,
umls-concept:C0389071,
umls-concept:C0752046,
umls-concept:C1335858,
umls-concept:C1519249,
umls-concept:C2603343
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pubmed:issue |
4
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pubmed:dateCreated |
2009-6-22
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pubmed:abstractText |
The adiponectin promoter single nucleotide polymorphism (SNP) -11391G/A is found to be associated with nephropathy in type 1 diabetic (T1D) patients among Danish, but not French, Finnish, and Swedish populations. In the present study, we identified the binding sites for transcriptional factors in the adiponectin promoter region and also evaluated the association between adiponectin promoter polymorphisms and diabetic nephropathy (DN) in T1D patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1873-460X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
265-72
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pubmed:meshHeading |
pubmed-meshheading:18599322-Adult,
pubmed-meshheading:18599322-Base Sequence,
pubmed-meshheading:18599322-Binding Sites,
pubmed-meshheading:18599322-Case-Control Studies,
pubmed-meshheading:18599322-Denmark,
pubmed-meshheading:18599322-Diabetes Mellitus, Type 1,
pubmed-meshheading:18599322-Diabetic Nephropathies,
pubmed-meshheading:18599322-Female,
pubmed-meshheading:18599322-Gene Frequency,
pubmed-meshheading:18599322-Genetic Predisposition to Disease,
pubmed-meshheading:18599322-Genotype,
pubmed-meshheading:18599322-Humans,
pubmed-meshheading:18599322-Immunoglobulins,
pubmed-meshheading:18599322-Male,
pubmed-meshheading:18599322-Middle Aged,
pubmed-meshheading:18599322-Molecular Sequence Data,
pubmed-meshheading:18599322-Polymorphism, Single Nucleotide,
pubmed-meshheading:18599322-Promoter Regions, Genetic,
pubmed-meshheading:18599322-Receptors, Adiponectin
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pubmed:articleTitle |
A single nucleotide polymorphism alters the sequence of SP1 binding site in the adiponectin promoter region and is associated with diabetic nephropathy among type 1 diabetic patients in the Genetics of Kidneys in Diabetes Study.
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pubmed:affiliation |
Department of Molecular Medicine and Surgery, Rolf Luft Center for Diabetes Research, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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