Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2008-8-4
pubmed:abstractText
During the development of blood vascular systems in the masseter muscle, one functional property of the blood supply via capillaries is altered by the change in feeding pattern from suckling to mastication. The lymphatic vessel hyaluronan receptor-1 (LYVE-1) is a marker of lymphatic endothelial cells. The PECAM (CD31) is also an important marker of vascular endothelial cells and lymphatic cells. The mechanisms by which circulating lymphatic endothelial cells from blood vessels in masseter muscle form a network of lymphatic capillaries and vessels functioning in jaw muscle movement remain unknown. In our results, LYVE-1- and CD31- positive reactions were located in almost identical regions at the stages examined using double immunofluorescence staining. However, the level of protein for LYVE-1 and CD31 differed between superficial and deep regions in postnatal rat masseter muscle using Western blotting analysis. The different distribution of LYVE-1 and CD31 antibody reactions was found in the deep region in contrast to that of the superficial area in 3-7-week-old rat masseter muscles. Concomitant with the increased level of protein for CD31 in the deep region, many small vessels branch in this region during development in rat masseter muscle. Therefore, different levels of protein and immunohistochemical reactions for CD31- and LYVE-1-positive cells may reflect alterations in the functional properties of the blood supply and collection via capillaries due to the changes in feeding pattern.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0940-9602
pubmed:author
pubmed:issnType
Print
pubmed:volume
190
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
329-38
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Distribution of LYVE-1 and CD31 in postnatal rat masseter muscle.
pubmed:affiliation
Department of Anatomy, School of Life Dentistry at Tokyo, Nippon Dental University, 1-9-20 Fujimi, Chiyoda-ku, Tokyo, Japan. iwaoa1@tokyo.ndu.ac.jp
pubmed:publicationType
Journal Article