rdf:type |
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lifeskim:mentions |
umls-concept:C0011860,
umls-concept:C0035647,
umls-concept:C0205214,
umls-concept:C0205419,
umls-concept:C0337696,
umls-concept:C0750502,
umls-concept:C1171304,
umls-concept:C1277063,
umls-concept:C1335238,
umls-concept:C1420644,
umls-concept:C1524069,
umls-concept:C1825577,
umls-concept:C1882417,
umls-concept:C1970415
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pubmed:dateCreated |
2008-7-23
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pubmed:abstractText |
Recent genome-wide association (GWA) studies have identified several unsuspected genes associated with type 2 diabetes (T2D) with previously unknown functions. In this investigation, we have examined the role of 9 most significant SNPs reported in GWA studies: [peroxisome proliferator-activated receptor gamma 2 (PPARG2; rs 1801282); insulin-like growth factor two binding protein 2 (IGF2BP2; rs 4402960); cyclin-dependent kinase 5, a regulatory subunit-associated protein1-like 1 (CDK5; rs7754840); a zinc transporter and member of solute carrier family 30 (SLC30A8; rs13266634); a variant found near cyclin-dependent kinase inhibitor 2A (CDKN2A; rs10811661); hematopoietically expressed homeobox (HHEX; rs 1111875); transcription factor-7-like 2 (TCF7L2; rs 10885409); potassium inwardly rectifying channel subfamily J member 11(KCNJ11; rs 5219); and fat mass obesity-associated gene (FTO; rs 9939609)].
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pubmed:grant |
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598350-10404798,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/18598350-9891060
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:issn |
1471-2350
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pubmed:author |
pubmed-author:FerrellRobert ERE,
pubmed-author:HanShizhongS,
pubmed-author:KambohMohammed IMI,
pubmed-author:MehraNarinder KNK,
pubmed-author:MulvihillJohn JJJ,
pubmed-author:NathSwapan KSK,
pubmed-author:OrtegaLydaL,
pubmed-author:RalhanSarju KSK,
pubmed-author:SangheraDharambir KDK,
pubmed-author:SinghJairupJ,
pubmed-author:WanderGurpreet SGS
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pubmed:issnType |
Electronic
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
59
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
|