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rdf:type |
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lifeskim:mentions |
umls-concept:C0011399,
umls-concept:C0026850,
umls-concept:C0038250,
umls-concept:C0040455,
umls-concept:C0040732,
umls-concept:C0086418,
umls-concept:C0205252,
umls-concept:C0205276,
umls-concept:C0205373,
umls-concept:C0324430,
umls-concept:C1280551
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pubmed:dateCreated |
2008-9-5
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pubmed:abstractText |
The golden retriever muscular dystrophy (GRMD) dogs represent the best available animal model for therapeutic trials aiming at the future treatment of human Duchenne muscular dystrophy (DMD). We have obtained a rare litter of six GRMD dogs (3 males and 3 females) born from an affected male and a carrier female which were submitted to a therapeutic trial with adult human stem cells to investigate their capacity to engraft into dogs muscles by local as compared to systemic injection without any immunosuppression.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-10376903,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-10517639,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-11776472,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-11944998,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-11986244,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-12491947,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-12589164,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-13768451,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-15268726,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-15328150,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-1536178,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-15601570,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-1577476,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-15820948,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-16210973,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-16923606,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-16989735,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-17108972,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-17137828,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-17306535,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-17409736,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-17475492,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-17518650,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-17606437,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-17685479,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-18079433,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-18216690,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-1865908,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-2072118,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18598348-7887428
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1479-5876
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pubmed:author |
pubmed-author:AmbrosioCarlos ECE,
pubmed-author:BrolioMarina PMP,
pubmed-author:CabralRosa MRM,
pubmed-author:FonsecaSimone A SSA,
pubmed-author:GaiadThais PTP,
pubmed-author:KerkisAlexandreA,
pubmed-author:KerkisIrinaI,
pubmed-author:MarandubaCarlos M CCM,
pubmed-author:MartinsDaniele SDS,
pubmed-author:MiglinoMaria AMA,
pubmed-author:MoriniAdriana CAC,
pubmed-author:Sant'AnnaOsvaldo AOA,
pubmed-author:VieiraNatassia MNM,
pubmed-author:ZatzMayanaM,
pubmed-author:ZucconiEderE
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pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
35
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18598348-Animals,
pubmed-meshheading:18598348-Cell Differentiation,
pubmed-meshheading:18598348-Cell Movement,
pubmed-meshheading:18598348-Cells, Cultured,
pubmed-meshheading:18598348-Child,
pubmed-meshheading:18598348-Child, Preschool,
pubmed-meshheading:18598348-Dental Pulp,
pubmed-meshheading:18598348-Dog Diseases,
pubmed-meshheading:18598348-Dogs,
pubmed-meshheading:18598348-Dystrophin,
pubmed-meshheading:18598348-Fluorescent Antibody Technique,
pubmed-meshheading:18598348-Genotype,
pubmed-meshheading:18598348-Humans,
pubmed-meshheading:18598348-Mice,
pubmed-meshheading:18598348-Muscle, Skeletal,
pubmed-meshheading:18598348-Muscle Development,
pubmed-meshheading:18598348-Muscular Dystrophy, Animal,
pubmed-meshheading:18598348-Stem Cell Transplantation,
pubmed-meshheading:18598348-Tooth, Deciduous
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pubmed:year |
2008
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pubmed:articleTitle |
Early transplantation of human immature dental pulp stem cells from baby teeth to golden retriever muscular dystrophy (GRMD) dogs: Local or systemic?
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pubmed:affiliation |
Laboratório de Genética e Imunoquímica, Instituto Butantan, São Paulo, Brasil. ikerkis@butantan.gov.br
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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