Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7-8
pubmed:dateCreated
2008-8-1
pubmed:abstractText
Although many questions are still debated, some recommendations can be formulated regarding the use of neuromuscular blocking agents in the ICU. A transient curarization can be used during brief diagnostic or therapeutic procedures in order to avoid haemodynamic consequences of deep sedation. A volume controlled ventilation has to be used during the procedure. In ARDS patients, a prolonged curarization of 48 h or more is beneficial regarding systemic oxygenation, even in patients well adapted to their ventilator. The use of cisatracurium should be recommended in this context. The depth of curarization has to be checked by using a train of four stimulation at the corugator supercilii with an endpoint of 2/4 responses. A recovery from curarization should be daily envisaged if possible, in order to check the depth of the underlying sedation. In brain injured patients, a curarization can be envisaged if adaptation to the ventilator remains difficult or if normothermia or moderate hypothermia, if indicated, cannot be obtained. However, these attitudes are not based on specific data at the present time.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1769-6623
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
567-73
pubmed:meshHeading
pubmed-meshheading:18595649-Adult, pubmed-meshheading:18595649-Atracurium, pubmed-meshheading:18595649-Brain Injuries, pubmed-meshheading:18595649-Conscious Sedation, pubmed-meshheading:18595649-Drug Administration Schedule, pubmed-meshheading:18595649-Drug Interactions, pubmed-meshheading:18595649-Drug Monitoring, pubmed-meshheading:18595649-Hemodynamics, pubmed-meshheading:18595649-Humans, pubmed-meshheading:18595649-Hyaline Membrane Disease, pubmed-meshheading:18595649-Hypnotics and Sedatives, pubmed-meshheading:18595649-Infant, pubmed-meshheading:18595649-Infant, Newborn, pubmed-meshheading:18595649-Intensive Care, pubmed-meshheading:18595649-Neuromuscular Nondepolarizing Agents, pubmed-meshheading:18595649-Oxygen Consumption, pubmed-meshheading:18595649-Pneumothorax, pubmed-meshheading:18595649-Randomized Controlled Trials as Topic, pubmed-meshheading:18595649-Respiration, Artificial, pubmed-meshheading:18595649-Respiratory Distress Syndrome, Adult, pubmed-meshheading:18595649-Respiratory Muscles
pubmed:articleTitle
[Indications and uses of neuromuscular blocking agents in the ICU].
pubmed:affiliation
Service d'anesthésie-réanimation, CHU Henri-Mondor, université Paris-12, 51, avenue du Mal-de-Lattre-de-Tassigny, 94000 Créteil, France. lagneauf@wanadoo.fr
pubmed:publicationType
Journal Article, English Abstract, Consensus Development Conference