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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
23
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pubmed:dateCreated |
2008-7-2
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pubmed:abstractText |
A 39-year-old male underwent distal gastrectomy for a high grade gastrointestinal stromal tumor (GIST). Computed tomography (CT) and magnetic resonance imaging (MRI) 107 mo after the operation, revealed a cystic mass (14 cm in diameter) and a solid mass (9 cm in diameter) in the right and left lobes of the liver, respectively. A biopsy specimen of the solid mass showed a liver metastasis of GIST. The patient received imatinib mesylate (IM) treatment, 400 mg/day orally. Following the IM treatment for a period of 35 mo, the patient underwent partial hepatectomy (S4 + S5). The effect of IM on the metastatic lesions was interpreted as pathologic complete response (CR). Pathologically verified cases showing therapeutic efficacy of IM have been rarely reported.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-11287975,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-11573047,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-12181401,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-12888812,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-14605627,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-14672776,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-15451219,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-15735135,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-15900603,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-15928191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-16531543,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-16858179,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-16957966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-17072676,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-17435538,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-17435539,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18595147-9438854
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1007-9327
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pubmed:author |
pubmed-author:HosoneMasaruM,
pubmed-author:LiuAiminA,
pubmed-author:MaedaShotaroS,
pubmed-author:MaruyamaHiroshiH,
pubmed-author:MatsutaniTakeshiT,
pubmed-author:MiyamotoMasayukiM,
pubmed-author:SasajimaKojiK,
pubmed-author:SuzukiSeijiS,
pubmed-author:TajiriTakashiT,
pubmed-author:WatanabeHidehiroH,
pubmed-author:YokoyamaTadashiT
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pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3763-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18595147-Administration, Oral,
pubmed-meshheading:18595147-Adult,
pubmed-meshheading:18595147-Antineoplastic Agents,
pubmed-meshheading:18595147-Chemotherapy, Adjuvant,
pubmed-meshheading:18595147-Gastrectomy,
pubmed-meshheading:18595147-Gastrointestinal Stromal Tumors,
pubmed-meshheading:18595147-Hepatectomy,
pubmed-meshheading:18595147-Humans,
pubmed-meshheading:18595147-Liver Neoplasms,
pubmed-meshheading:18595147-Magnetic Resonance Imaging,
pubmed-meshheading:18595147-Male,
pubmed-meshheading:18595147-Neoadjuvant Therapy,
pubmed-meshheading:18595147-Piperazines,
pubmed-meshheading:18595147-Protein Kinase Inhibitors,
pubmed-meshheading:18595147-Pyrimidines,
pubmed-meshheading:18595147-Tomography, X-Ray Computed,
pubmed-meshheading:18595147-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
Pathologic complete response confirmed by surgical resection for liver metastases of gastrointestinal stromal tumor after treatment with imatinib mesylate.
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pubmed:affiliation |
Department of Surgery, Tama-Nagayama Hospital, Nippon Medical School, 1-7-1 Nagayama, Tama, Tokyo 206-8512, Japan. seiji@nms.ac.jp
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pubmed:publicationType |
Journal Article,
Case Reports
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