|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
13
|
|
pubmed:dateCreated |
2008-7-2
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|
pubmed:abstractText |
Exposing human tumor cells to sublethal doses of external beam radiation up-regulates expression of tumor antigen and accessory molecules, rendering tumor cells more susceptible to killing by antigen-specific CTLs. This study explored the possibility that exposure to palliative doses of a radiopharmaceutical agent could alter the phenotype of tumor cells to render them more susceptible to T cell-mediated killing.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
1078-0432
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:day |
1
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
4241-9
|
|
pubmed:meshHeading |
pubmed-meshheading:18594006-Breast Neoplasms,
pubmed-meshheading:18594006-Cell Line, Tumor,
pubmed-meshheading:18594006-Cell Separation,
pubmed-meshheading:18594006-Female,
pubmed-meshheading:18594006-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18594006-Humans,
pubmed-meshheading:18594006-Lung Neoplasms,
pubmed-meshheading:18594006-Male,
pubmed-meshheading:18594006-Organometallic Compounds,
pubmed-meshheading:18594006-Organophosphorus Compounds,
pubmed-meshheading:18594006-Phenotype,
pubmed-meshheading:18594006-Prostatic Neoplasms,
pubmed-meshheading:18594006-Radioisotopes,
pubmed-meshheading:18594006-Samarium,
pubmed-meshheading:18594006-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:18594006-Treatment Outcome
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|
pubmed:year |
2008
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|
pubmed:articleTitle |
The use of chelated radionuclide (samarium-153-ethylenediaminetetramethylenephosphonate) to modulate phenotype of tumor cells and enhance T cell-mediated killing.
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|
pubmed:affiliation |
Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Intramural
|
