rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-7-2
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pubmed:abstractText |
Despite efforts to elucidate both the molecular mechanism and the clinical predictors of vasospasm after aneurysmal subarachnoid hemorrhage (ASAH), its pathogenesis remains unclear. Monocyte chemoattractant protein-1 (MCP-1) is a chemokine that has been firmly implicated in the pathophysiology of vasospasm and in neural tissue injury following focal ischemia in both animal models and human studies. The authors hypothesized that MCP-1 would be found in increased concentrations in the blood and cerebrospinal fluid (CSF) of patients with ASAH and would correlate with both outcome and the occurrence of vasospasm.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-3085
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pubmed:author |
pubmed-author:ConnollyE SanderESJr,
pubmed-author:DesantisBrianna MBM,
pubmed-author:HahnDavid KDK,
pubmed-author:KellnerChristopher PCP,
pubmed-author:KimGrace HGH,
pubmed-author:KomotarRicardo JRJ,
pubmed-author:MayerStephan ASA,
pubmed-author:MusabbirMuhithM,
pubmed-author:OttenMarc LML,
pubmed-author:RynkowskiMichalM,
pubmed-author:SchmidtJ MichaelJM,
pubmed-author:SciaccaRobertR,
pubmed-author:StarkeRobert MRM
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pubmed:issnType |
Print
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
38-43
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pubmed:meshHeading |
pubmed-meshheading:18593272-Adult,
pubmed-meshheading:18593272-Aged,
pubmed-meshheading:18593272-Case-Control Studies,
pubmed-meshheading:18593272-Chemokine CCL2,
pubmed-meshheading:18593272-Cohort Studies,
pubmed-meshheading:18593272-Female,
pubmed-meshheading:18593272-Humans,
pubmed-meshheading:18593272-Intracranial Aneurysm,
pubmed-meshheading:18593272-Male,
pubmed-meshheading:18593272-Middle Aged,
pubmed-meshheading:18593272-Predictive Value of Tests,
pubmed-meshheading:18593272-Severity of Illness Index,
pubmed-meshheading:18593272-Subarachnoid Hemorrhage,
pubmed-meshheading:18593272-Treatment Outcome,
pubmed-meshheading:18593272-Vasospasm, Intracranial
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pubmed:year |
2008
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pubmed:articleTitle |
Monocyte chemoattractant protein-1 predicts outcome and vasospasm following aneurysmal subarachnoid hemorrhage.
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pubmed:affiliation |
Department of Neurological Surgery, Columbia University, New York, New York 10032, USA. ghkim9@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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