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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1977-9-29
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pubmed:abstractText |
Mescaline, in concentrations of 5 x 10(-4) and 1 x 10(-3) M, produced negative chronotropic and positive inotropic responses in isolated, spontaneously beating rat atria. In tissues driven at a constant rate, the inotropic response was diminished greatly, indicating that the increment in the force of contraction was secondary to the reduction in rate. These chronotropic and inotropic responses were not altered consistently by pretreatment with the histamine antagonists chlorpheniramine and metiamide.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
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pubmed:issn |
0022-3549
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
66
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
938-41
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:18592-Animals,
pubmed-meshheading:18592-Electric Stimulation,
pubmed-meshheading:18592-Female,
pubmed-meshheading:18592-Heart,
pubmed-meshheading:18592-Heart Rate,
pubmed-meshheading:18592-Histamine H1 Antagonists,
pubmed-meshheading:18592-Histamine H2 Antagonists,
pubmed-meshheading:18592-Male,
pubmed-meshheading:18592-Mescaline,
pubmed-meshheading:18592-Myocardial Contraction,
pubmed-meshheading:18592-Rats
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pubmed:year |
1977
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pubmed:articleTitle |
Actions of mescaline on isolated rat atria.
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pubmed:publicationType |
Journal Article,
In Vitro
|