Linked Life Data

18592223

Source:http://linkedlifedata.com/resource/pubmed/id/18592223

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-8-15
pubmed:abstractText
Recently, it was shown that patients have different functional activation patterns within affected primary sensorimotor cortex (SMC) after intensive rehabilitation therapy. This individual difference was supposed to depend on the integrity of the cortico-spinal fibres from the primary motor cortex. In this study, we considered whether patients with different fMRI activation patterns after intensive rehabilitation therapy suffered from different cortico-spinal fibre lesions. To comprehend this circumstance a lesion subtraction analysis was used. To verify these results with the use of transcranial magnetic stimulation motor evoked potentials was also derived. Patients were treated after a modified version of constraint-induced movement therapy (modCIMT; 3 h daily for 4 weeks). Increased and decreased SMC activation showed similar individual patterns as described previously. These activation differences depend on the integrity of the cortico-spinal tract, which was measured via lesion subtraction analysis between patient groups, and was supported by affected motor evoked potentials.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1432-1106
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
190
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
329-36
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
The effect of cortico-spinal tract damage on primary sensorimotor cortex activation after rehabilitation therapy.
pubmed:affiliation
Department of Neurology, University Clinic Freiburg, Breisacherstrasse 64, 79106 Freiburg im Breisgau, Germany. farsin.hamzei@uniklinik-freiburg.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't