Source:http://linkedlifedata.com/resource/pubmed/id/18589426
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-1-26
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pubmed:abstractText |
Increasing age is associated with reduced numbers of circulating endothelial progenitor cells (EPCs). It is unclear whether this relates to depletion or impairment of bone marrow progenitors, or to deficient mobilization signals from aging tissues. In cardiac transplant patients, one previous study has reported an association between circulating EPCs and the risk of cardiac allograft vasculopathy (CAV). We investigated whether increased donor heart age, a strong risk factor for CAV, was associated with reduced circulating EPC numbers in a group of cardiac transplant recipients matched for factors which influence EPC numbers, but with maximally discordant donor heart ages.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1879-1484
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
202
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
612-6
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pubmed:meshHeading |
pubmed-meshheading:18589426-Adult,
pubmed-meshheading:18589426-Age Distribution,
pubmed-meshheading:18589426-Aged,
pubmed-meshheading:18589426-Cell Count,
pubmed-meshheading:18589426-Cohort Studies,
pubmed-meshheading:18589426-Endothelium, Vascular,
pubmed-meshheading:18589426-Female,
pubmed-meshheading:18589426-Flow Cytometry,
pubmed-meshheading:18589426-Heart Transplantation,
pubmed-meshheading:18589426-Hematopoietic Stem Cells,
pubmed-meshheading:18589426-Humans,
pubmed-meshheading:18589426-Male,
pubmed-meshheading:18589426-Middle Aged,
pubmed-meshheading:18589426-Postoperative Complications,
pubmed-meshheading:18589426-Risk Factors,
pubmed-meshheading:18589426-Tissue Donors,
pubmed-meshheading:18589426-Transplantation, Homologous,
pubmed-meshheading:18589426-Vascular Diseases
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pubmed:year |
2009
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pubmed:articleTitle |
Circulating endothelial progenitor cell numbers are not associated with donor organ age or allograft vasculopathy in cardiac transplant recipients.
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pubmed:affiliation |
University of Newcastle, Newcastle Upon Tyne, United Kingdom. H.E.Thomas@ncl.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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