Source:http://linkedlifedata.com/resource/pubmed/id/18586428
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3 Suppl
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pubmed:dateCreated |
2008-12-1
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pubmed:abstractText |
Contrast enhancement by refraction was used to visualize tumours in the rabbit lung. VX2 tumour cells were intravenously injected into a rabbit. After 14 days the rabbit was euthanized and the lungs were imaged. Refraction-enhanced X-ray images were obtained with a sample-to-detector distance of 2.65-6m. The beamline BL20B2 at the SPring-8 synchrotron radiation facility was used for the experiment, with a monochromatic X-ray beam with an energy of 33.2 keV. In the case of projection images, it was found that refraction did not help visualization of small tumours: the nodules did not show up with sharply defined edges. In tomography, tumours with a size of 1-10mm were clearly visualized, together with blood vessels with a diameter down to 0.4mm. These results show that refraction-enhanced imaging may be useful in human lung tomography to find small tumours.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1872-7727
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S54-7
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pubmed:meshHeading |
pubmed-meshheading:18586428-Algorithms,
pubmed-meshheading:18586428-Animals,
pubmed-meshheading:18586428-Female,
pubmed-meshheading:18586428-Imaging, Three-Dimensional,
pubmed-meshheading:18586428-Lung,
pubmed-meshheading:18586428-Lung Neoplasms,
pubmed-meshheading:18586428-Rabbits,
pubmed-meshheading:18586428-Radiographic Image Enhancement,
pubmed-meshheading:18586428-Radiographic Image Interpretation, Computer-Assisted,
pubmed-meshheading:18586428-Refractometry,
pubmed-meshheading:18586428-Reproducibility of Results,
pubmed-meshheading:18586428-Sensitivity and Specificity,
pubmed-meshheading:18586428-Tomography, X-Ray
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pubmed:year |
2008
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pubmed:articleTitle |
High-resolution visualization of tumours in rabbit lung using refraction contrast X-ray imaging.
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pubmed:affiliation |
Japan Synchrotron Radiation Research Institute, SPring-8, 1-1-1 Kouto, Sayo, Hyogo 679-5198, Japan. sera@riken.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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