Linked Life Data

18582485

Source:http://linkedlifedata.com/resource/pubmed/id/18582485

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-8-1
pubmed:abstractText
Species-specific antibodies (Abs) to venoms from two species of the genus Echis were prepared by adsorption of monovalent and affinity purified anti-Echis Abs to the heterologous venom matrices (VMs). The avidity of the Abs to the homologous and the heterologous venoms is constantly ranked in the order; monovalent Ab>cross-reactive Ab>species-specific Ab. The avidity of the species-specific Abs to the homologous venoms of Echis coloratus (Eco) and Echis carinatus pyramidum (Epy) were 1.20+/-0.26 and 1.10+/-0.29, respectively. The avidity of the species-specific Abs to the heterologous venoms was too low to be detected. These results demonstrate for the first time that the avidity can be used to discriminate the immunologically high cross-reactive venoms. The discrimination of (14/14) venom samples of the two species on avidity bases confirmed the reliability and the specificity of the assay.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0041-0101
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
49-54
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Avidity based discrimination of venoms from two Egyptian Echis species.
pubmed:affiliation
Department of Molecular Biology National Research Center, Tahrir Street, Dokki, Cairo, Egypt. afwahby@hotmail.com
pubmed:publicationType
Journal Article