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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-7-16
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pubmed:abstractText |
In hospital-based studies, alpha(+)-thalassemia has been found to protect against severe, life-threatening falciparum malaria. alpha(+)-Thalassemia does not seem to prevent infection or high parasite densities but rather limits progression to severe disease--in particular, severe malarial anemia. We assessed to what extent alpha(+)-thalassemia influences the association between mild, asymptomatic Plasmodium falciparum infection and hemoglobin concentration.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-1899
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pubmed:author |
pubmed-author:Andang'oPauline E APE,
pubmed-author:KraaijenhagenRob JRJ,
pubmed-author:MbugiErasto VEV,
pubmed-author:MockenhauptFrank PFP,
pubmed-author:MwanikiDavid LDL,
pubmed-author:OlomiRaimos MRM,
pubmed-author:RoewerSusanneS,
pubmed-author:SavelkoulHuub F JHF,
pubmed-author:ShaoJohn FJF,
pubmed-author:VeenemansJacobienJ,
pubmed-author:VerhoefHansH,
pubmed-author:van der MeerJos W MJW
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
198
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
401-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18582194-Anemia,
pubmed-meshheading:18582194-Animals,
pubmed-meshheading:18582194-Child,
pubmed-meshheading:18582194-Child, Preschool,
pubmed-meshheading:18582194-Globins,
pubmed-meshheading:18582194-Hemoglobins,
pubmed-meshheading:18582194-Humans,
pubmed-meshheading:18582194-Immunity, Innate,
pubmed-meshheading:18582194-Infant,
pubmed-meshheading:18582194-Kenya,
pubmed-meshheading:18582194-Malaria,
pubmed-meshheading:18582194-Tanzania,
pubmed-meshheading:18582194-alpha-Thalassemia
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pubmed:year |
2008
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pubmed:articleTitle |
Alpha+ -thalassemia protects against anemia associated with asymptomatic malaria: evidence from community-based surveys in Tanzania and Kenya.
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pubmed:affiliation |
Cell Biology and Immunology Group, Wageningen University, Wageningen, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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