18580597

Source:http://linkedlifedata.com/resource/pubmed/id/18580597

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0002395, umls-concept:C0009429, umls-concept:C0443252, umls-concept:C0556895, umls-concept:C0750729, umls-concept:C1280519
pubmed:issue	3
pubmed:dateCreated	2008-9-4
pubmed:abstractText	To compare the real-world clinical effectiveness and long-term clinical trajectory in patients with Alzheimer disease (AD) treated with combination (COMBO) therapy consisting of cholinesterase-inhibitor (CI) plus memantine (MEM) versus CI alone versus no treatment with either.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/1K23 AG27171-01, http://linkedlifedata.com/resource/pubmed/grant/5P50 AG05134, http://linkedlifedata.com/resource/pubmed/grant/K23 AG027171-01A1, http://linkedlifedata.com/resource/pubmed/grant/P50 AG005134-259001
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8704771
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Cholinesterase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Dopamine Agents, http://linkedlifedata.com/resource/pubmed/chemical/Memantine
pubmed:status	MEDLINE
pubmed:issn	1546-4156
pubmed:author	pubmed-author:AtriAlirezaA, pubmed-author:GrowdonJohn HJH, pubmed-author:LocascioJoseph JJJ, pubmed-author:ShaughnessyLynn WLW
pubmed:issnType	Electronic
pubmed:volume	22
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	209-21
pubmed:dateRevised	2011-9-26
pubmed:meshHeading	pubmed-meshheading:18580597-Activities of Daily Living, pubmed-meshheading:18580597-Aged, pubmed-meshheading:18580597-Alzheimer Disease, pubmed-meshheading:18580597-Cholinesterase Inhibitors, pubmed-meshheading:18580597-Cognition, pubmed-meshheading:18580597-Cognition Disorders, pubmed-meshheading:18580597-Dopamine Agents, pubmed-meshheading:18580597-Drug Therapy, Combination, pubmed-meshheading:18580597-Female, pubmed-meshheading:18580597-Humans, pubmed-meshheading:18580597-Male, pubmed-meshheading:18580597-Memantine, pubmed-meshheading:18580597-Time, pubmed-meshheading:18580597-Treatment Outcome
pubmed:articleTitle	Long-term course and effectiveness of combination therapy in Alzheimer disease.
pubmed:affiliation	Department of Neurology and Massachusetts Alzheimer's Disease Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. aatri@partners.org
pubmed:publicationType	Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural