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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-6-26
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pubmed:abstractText |
The polymorphism of the protein tyrosine phosphatase nonreceptor 22 (PTPN22) gene, which encodes an important negative regulator of T cell activation, has been reported to be associated with susceptibility to Graves' disease (GD) in Caucasians. The objective of this study was to investigate whether PTPN22 gene polymorphisms confer susceptibility to GD and Graves' ophthalmopathy (GO) in a Japanese population.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1050-7256
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
625-30
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pubmed:meshHeading |
pubmed-meshheading:18578611-Adolescent,
pubmed-meshheading:18578611-Adult,
pubmed-meshheading:18578611-Aged,
pubmed-meshheading:18578611-Aged, 80 and over,
pubmed-meshheading:18578611-Alleles,
pubmed-meshheading:18578611-Case-Control Studies,
pubmed-meshheading:18578611-Child,
pubmed-meshheading:18578611-Female,
pubmed-meshheading:18578611-Gene Frequency,
pubmed-meshheading:18578611-Genetic Predisposition to Disease,
pubmed-meshheading:18578611-Graves Disease,
pubmed-meshheading:18578611-Graves Ophthalmopathy,
pubmed-meshheading:18578611-Humans,
pubmed-meshheading:18578611-Japan,
pubmed-meshheading:18578611-Linkage Disequilibrium,
pubmed-meshheading:18578611-Male,
pubmed-meshheading:18578611-Middle Aged,
pubmed-meshheading:18578611-Polymorphism, Single Nucleotide,
pubmed-meshheading:18578611-Protein Tyrosine Phosphatase, Non-Receptor Type 22
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pubmed:year |
2008
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pubmed:articleTitle |
Associations of protein tyrosine phosphatase nonreceptor 22 (PTPN22) gene polymorphisms with susceptibility to Graves' disease in a Japanese population.
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pubmed:affiliation |
Division of Endocrinology and Metabolism, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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