Source:http://linkedlifedata.com/resource/pubmed/id/18577653
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
2008-6-25
|
| pubmed:abstractText |
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute severe blistering diseases of the skin and also two of the most devastating ocular surface diseases leading to corneal damage and loss of vision. The extreme rarity of cutaneous and ocular surface reactions to drug therapies led us to suspect individual susceptibility. SJS/TEN patients in the acute stage were reported to manifest increased serum levels of Fas Ligand (FasL). Thus, we performed SNP association analysis of the FasL gene.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
1468-2079
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
92
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
989-91
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| pubmed:meshHeading |
pubmed-meshheading:18577653-Adult,
pubmed-meshheading:18577653-Aged,
pubmed-meshheading:18577653-Case-Control Studies,
pubmed-meshheading:18577653-Epidermal Necrolysis, Toxic,
pubmed-meshheading:18577653-Fas Ligand Protein,
pubmed-meshheading:18577653-Gene Frequency,
pubmed-meshheading:18577653-Genetic Predisposition to Disease,
pubmed-meshheading:18577653-Humans,
pubmed-meshheading:18577653-Middle Aged,
pubmed-meshheading:18577653-Polymorphism, Single Nucleotide,
pubmed-meshheading:18577653-Stevens-Johnson Syndrome
|
| pubmed:year |
2008
|
| pubmed:articleTitle |
Association of Fas Ligand gene polymorphism with Stevens-Johnson syndrome.
|
| pubmed:affiliation |
Department of Ophthalmology, Kyoto Prefectural University of Medicine, Hirokoji, Kawaramachi, Kamigyoku, Kyoto 602-0841, Japan. mueta@ophth.kpu-m.ac.jp
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|