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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2008-7-15
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pubmed:abstractText |
To determine whether genetic variants of the PTPN22 gene, including the R620W (1858C>T) missense single-nucleotide polymorphism (SNP), are associated with systemic sclerosis (SSc). Since PTPN22 is involved in multiple autoimmune diseases, we also examined the occurrence of a concomitant autoimmune disease. We then conducted a meta-analysis of the most recent studies of SSc in order to verify the association or lack of association between the PTPN22 1858C>T variant and SSc.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0004-3591
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pubmed:author |
pubmed-author:AllanoreYY,
pubmed-author:AvouacJJ,
pubmed-author:BoileauCC,
pubmed-author:CabaneJJ,
pubmed-author:DieudéPP,
pubmed-author:GRAYD HDH,
pubmed-author:GranelBB,
pubmed-author:GuedjMM,
pubmed-author:HachullaEE,
pubmed-author:KahanAA,
pubmed-author:MeyerOO,
pubmed-author:MouthonLL,
pubmed-author:SibiliaJJ,
pubmed-author:WipffJJ
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pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2183-8
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pubmed:meshHeading |
pubmed-meshheading:18576360-Aged,
pubmed-meshheading:18576360-Alleles,
pubmed-meshheading:18576360-Case-Control Studies,
pubmed-meshheading:18576360-European Continental Ancestry Group,
pubmed-meshheading:18576360-Female,
pubmed-meshheading:18576360-France,
pubmed-meshheading:18576360-Genetic Predisposition to Disease,
pubmed-meshheading:18576360-Humans,
pubmed-meshheading:18576360-Male,
pubmed-meshheading:18576360-Middle Aged,
pubmed-meshheading:18576360-Mutation, Missense,
pubmed-meshheading:18576360-Polymorphism, Single Nucleotide,
pubmed-meshheading:18576360-Protein Tyrosine Phosphatase, Non-Receptor Type 22,
pubmed-meshheading:18576360-Scleroderma, Systemic
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pubmed:year |
2008
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pubmed:articleTitle |
The PTPN22 620W allele confers susceptibility to systemic sclerosis: findings of a large case-control study of European Caucasians and a meta-analysis.
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pubmed:affiliation |
Université Paris 7, Paris, France. philippe.dieude@bch.aphp.fr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Meta-Analysis
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