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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2008-9-10
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pubmed:abstractText |
Gene expression profiling has the potential to enhance current methods for the diagnosis of haematological malignancies. Here, we present data on 204 analyses from an international standardization programme that was conducted in 11 laboratories as a prephase to the Microarray Innovations in LEukemia (MILE) study. Each laboratory prepared two cell line samples, together with three replicate leukaemia patient lysates in two distinct stages: (i) a 5-d course of protocol training, and (ii) independent proficiency testing. Unsupervised, supervised, and r(2) correlation analyses demonstrated that microarray analysis can be performed with remarkably high intra-laboratory reproducibility and with comparable quality and reliability.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1365-2141
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pubmed:author |
pubmed-author:BassoGiuseppeG,
pubmed-author:ChiarettiSabinaS,
pubmed-author:De VosJohnJ,
pubmed-author:Dell'ortoMarta CampoMC,
pubmed-author:DowningJames RJR,
pubmed-author:FoàRobinR,
pubmed-author:GilkesAmanda FAF,
pubmed-author:HaferlachTorstenT,
pubmed-author:HernándezJesus MJM,
pubmed-author:HofmannWolf-KarstenWK,
pubmed-author:KippsThomas JTJ,
pubmed-author:KoayEvelyn SES,
pubmed-author:KohlmannAlexanderA,
pubmed-author:LiRachelR,
pubmed-author:LiuWei-MinWM,
pubmed-author:LumbrerasEvaE,
pubmed-author:MillsKen IKI,
pubmed-author:PapenhausenPeter RPR,
pubmed-author:RassentiLaura ZLZ,
pubmed-author:RauhutSonjaS,
pubmed-author:ShurtleffSheila ASA,
pubmed-author:WieczorekLotharL,
pubmed-author:WilliamsPaul MPM,
pubmed-author:YeohAllen EAE
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pubmed:issnType |
Electronic
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pubmed:volume |
142
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
802-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18573112-Adenocarcinoma,
pubmed-meshheading:18573112-Breast Neoplasms,
pubmed-meshheading:18573112-Carcinoma,
pubmed-meshheading:18573112-Europe,
pubmed-meshheading:18573112-Female,
pubmed-meshheading:18573112-Gene Expression Profiling,
pubmed-meshheading:18573112-Humans,
pubmed-meshheading:18573112-Leukemia,
pubmed-meshheading:18573112-Liver Neoplasms,
pubmed-meshheading:18573112-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:18573112-Pilot Projects,
pubmed-meshheading:18573112-RNA,
pubmed-meshheading:18573112-Reference Standards,
pubmed-meshheading:18573112-Reproducibility of Results,
pubmed-meshheading:18573112-Singapore,
pubmed-meshheading:18573112-United States
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pubmed:year |
2008
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pubmed:articleTitle |
An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: the Microarray Innovations in LEukemia study prephase.
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pubmed:affiliation |
Roche Molecular Systems, Inc., Department of Genomics and Oncology, Pleasanton, CA, USA. alexander.kohlmann@roche.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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