Linked Life Data

18572394

Source:http://linkedlifedata.com/resource/pubmed/id/18572394

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2008-7-8
pubmed:abstractText
Uterine sarcomas remain challenging tumours to manage and need multi-disciplinary care. This article reviews the surgical and adjuvant treatments for these tumours. The importance of surgical staging is discussed and the need for careful review of the pathology. Newer classifications will help to distinguish the different types as we now recognise that carcinosarcomas are most likely to be epithelial cancers rather then sarcomas. A critical discussion of the roles of both adjuvant chemotherapy and radiation are discussed. Some recent important trials have helped to give better evidence base on which to plan future treatment strategies. The routine place of adjuvant pelvic radiation seems limited as it only leads to improved local control. To date chemotherapy studies have equally failed to show a benefit. More trials are needed to address these issues. We cannot be complacent as we still see too high a relapse rate and new treatment approaches are required, investigation of the new targeted agents may offer a more promising return. Given their relative uncommonness, centralisation of care and discussion at multi-disciplinary tumour boards is essential. International collaboration is essential.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0936-6555
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
470-8
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
The management of uterine sarcomas.
pubmed:affiliation
Western Infirmary, and Beatson Oncology Centre, Gartnavel General Hospital, Great Western Road, Glasgow, Scotland, UK. nick.reed@ggc.scot.nhs.uk
pubmed:publicationType
Journal Article, Review