Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2008-6-23
pubmed:abstractText
Hypoxia inducible factor-1 alpha (HIF-1alpha) is a hypoxia-responsive factor, which commonly exists in the tissues of solid tumors. It plays crucial roles in maintaining cell energy metabolism, tumor angiogenesis and metastasis, cell proliferation and apoptosis. This study was to investigate the effect of silencing HIF-1alpha by RNA interference on the expression of matrix metalloproteinase-2 (MMP-2) in human cervical carcinoma HeLa cells, and to further explore the mechanism.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1000-467X
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
600-5
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
[Interference of HIF-1alpha by RNA reduces the expression of matrix metalloproteinase-2 in human cervical carcinoma HeLa cells].
pubmed:affiliation
Cancer Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P. R. China.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't