|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2008-6-23
|
|
pubmed:abstractText |
A heterodinucleotide comprising BVDU and Gemcitabine bound together by a 5',5'-pyrophospate bridge (BVDUp(2)dFdC) has been synthesized and evaluated as antitumor agent against AH13 rat sarcoma cells. BVDUp(2)dFdC showed a cytotoxicity similar to that of Gemcitabine.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
1525-7770
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
27
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
460-8
|
|
pubmed:meshHeading |
pubmed-meshheading:18569785-Animals,
pubmed-meshheading:18569785-Antimetabolites, Antineoplastic,
pubmed-meshheading:18569785-Antiviral Agents,
pubmed-meshheading:18569785-Bromodeoxyuridine,
pubmed-meshheading:18569785-Cell Line, Tumor,
pubmed-meshheading:18569785-Deoxycytidine,
pubmed-meshheading:18569785-Drug Screening Assays, Antitumor,
pubmed-meshheading:18569785-Rats,
pubmed-meshheading:18569785-Sarcoma, Experimental
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Synthesis and antitumor activity of a heterodinucleotide of BVDU and gemcitabine.
|
|
pubmed:affiliation |
Department of Chemical Sciences, University of Camerino, Camerino, Italy.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
