Linked Life Data

18569714

Source:http://linkedlifedata.com/resource/pubmed/id/18569714

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2008-6-23
pubmed:abstractText
Protection of human body against the harmful ultraviolet exposure is nowadays more important and interesting. Melanin, a group of bio-pigments, acts as a natural solar filter absorbing and reflecting most of the UV radiation passing through the layer of skin. Over production of the pigments can create a health problem, hyperpigmentation. Tyrosinase is a key enzyme, which catalyzes the conversion of L-tyrosine to L-dihydroxyalanine (L-Dopa), therefore tyrosinase inhibitors are used in various skin preparations due to its pronounced effect on anti-hyperpigment. In this study, an in vitro anti-tyrosinase activity study of the extracts from a hybrid Mulberry plant obtained from Morus alba L. and Morus rotundiloba Koidz, is shown to prove as new source of Thai whitening agent. The presence of betulinic acid, as an anti-inflammatory and anti-tyrosinase activity agent, is also reported. The study develops the technique of HPLC quantitation of betulinic acid and its relation to anti-tyrosinase activity of the whole parts of Thai Mulberry.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1478-6419
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
727-34
pubmed:dateRevised
2010-8-10
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
A new source of whitening agent from a Thai Mulberry plant and its betulinic acid quantitation.
pubmed:affiliation
Faculty of Pharmacy, Department of Pharmacognosy, Mahidol University, Thailand. herbsiam2003@yahoo.com
pubmed:publicationType
Journal Article, Validation Studies