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pubmed:abstractText |
No polymorphisms affecting serum FSH levels have been described in the human FSHB gene. We have identified a potential regulatory single nucleotide polymorphism (SNP, rs10835638; G/T) 211 bp upstream from the FSHB mRNA transcription start-site, located within a highly conserved region among placental mammals. We aimed to determine the correlation of carrier status of rs10835638 alternative alleles with serum FSH level in men, and testicular and hormonal parameters.
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pubmed:affiliation |
Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Riia Street 23, 51010 Tartu, Estonia.
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