Linked Life Data

18565639

Source:http://linkedlifedata.com/resource/pubmed/id/18565639

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2009-1-6
pubmed:abstractText
We applied multiple linear regression analysis to event-related electrophysiological responses to words and pseudowords in a visual lexical decision task, yielding event-related regression coefficients (ERRCs) instead of the traditional event-related potential (ERP) measure. Our main goal was to disentangle the earliest ERP effects of the length of letter strings ("word length") and orthographic neighbourhood size (Coltheart's "N"). With respect to N, existing evidence is still ambiguous with respect to whether effects of N reflect early access to lexico-semantic information, or whether they occur at later decision or verification stages. In the present study, we found distinct neurophysiological manifestations of both N and word length around 100ms after word onset. Importantly, the effect of N distinguished between words and pseudowords, while the effect of word length did not. Minimum norm source estimation revealed the most dominant sources for word length in bilateral posterior brain areas for both words and pseudowords. For N, these sources were more left-lateralised and consistent with perisylvian brain areas, with activation peaks in temporal areas being more anterior for words compared to pseudowords. Our results support evidence for an effect of N at early and elementary stages of word recognition. We discuss the implications of these results for the time line of word recognition processes, and emphasise the value of ERRCs in combination with source analysis in psycholinguistic and cognitive brain research.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1873-6246
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
64-74
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Can I have a quick word? Early electrophysiological manifestations of psycholinguistic processes revealed by event-related regression analysis of the EEG.
pubmed:affiliation
MRC Cognition and Brain Sciences Unit, Cambridge, UK. olaf.hauk@mrc-cbu.cam.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't