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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2008-6-19
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pubmed:abstractText |
The authors describe a dual tube/detector micro-computed tomography (micro-CT) system that has the potential to improve temporal resolution and material contrast in small animal imaging studies. To realize this potential, it is necessary to precisely calibrate the geometry of a dual micro-CT system to allow the combination of projection data acquired with each individual tube/detector in a single reconstructed image. The authors present a geometric calibration technique that uses multiple projection images acquired with the two imaging chains while rotating a phantom containing a vertical array of regularly spaced metallic beads. The individual geometries of the imaging chains are estimated from the phantom projection images using analytical methods followed by a refinement procedure based on nonlinear optimization. The geometric parameters are used to create the cone beam projection matrices required by the reconstruction process for each imaging chain. Next, a transformation between the two projection matrices is found that allows the combination of projection data in a single reconstructed image. The authors describe this technique, test it with a series of computer simulations, and then apply it to data collected from their dual tube/detector micro-CT system. The results demonstrate that the proposed technique is accurate, robust, and produces images free of misalignment artifacts.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-10659735,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-11021683,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-11098919,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-11385756,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-11695767,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-14552575,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-15651608,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-15651615,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-15895580,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-16105509,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-16507552,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-16827495,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-16872077,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-17255374,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-17555236,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-17558678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-17926967,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-8306301,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-8346283,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18561657-9725140
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0094-2405
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1820-9
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:18561657-Algorithms,
pubmed-meshheading:18561657-Animals,
pubmed-meshheading:18561657-Artifacts,
pubmed-meshheading:18561657-Calibration,
pubmed-meshheading:18561657-Equipment Design,
pubmed-meshheading:18561657-Humans,
pubmed-meshheading:18561657-Metals,
pubmed-meshheading:18561657-Mice,
pubmed-meshheading:18561657-Models, Statistical,
pubmed-meshheading:18561657-Models, Theoretical,
pubmed-meshheading:18561657-Phantoms, Imaging,
pubmed-meshheading:18561657-Radiographic Image Interpretation, Computer-Assisted,
pubmed-meshheading:18561657-Reproducibility of Results,
pubmed-meshheading:18561657-Tomography, X-Ray Computed,
pubmed-meshheading:18561657-Tomography Scanners, X-Ray Computed,
pubmed-meshheading:18561657-X-Rays
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pubmed:year |
2008
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pubmed:articleTitle |
Geometric calibration for a dual tube/detector micro-CT system.
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pubmed:affiliation |
Center for In Vivo Microscopy, Box 3302, Duke University Medical Center, Durham, North Carolina 27710, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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