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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-6-18
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pubmed:abstractText |
Prep1 and Pbx2 are the main homeodomain DNA-binding proteins of the TALE (three amino acid loop extension) family expressed in the thymus. We previously reported reduced Pbx2 expression and defective thymocyte maturation in Prep1 hypomorphic mice. To further investigate the role of this homeodomain DNA-binding protein in T cell development, we generated transgenic mice expressing the N-terminal fragment of Pbx1 (Pbx1NT) under the control of the Lck proximal promoter.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-10215622,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-10367898,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-11133839,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-12871956,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-15353558,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-16314502,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-16448541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-16515781,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-16847320,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-17904118,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-2123451,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-8527134,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18560600-8632000
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e2424
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18560600-Animals,
pubmed-meshheading:18560600-Base Sequence,
pubmed-meshheading:18560600-Cytosol,
pubmed-meshheading:18560600-DNA Primers,
pubmed-meshheading:18560600-Electrophoretic Mobility Shift Assay,
pubmed-meshheading:18560600-Flow Cytometry,
pubmed-meshheading:18560600-Homeodomain Proteins,
pubmed-meshheading:18560600-Mice,
pubmed-meshheading:18560600-Mice, Transgenic,
pubmed-meshheading:18560600-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18560600-S Phase,
pubmed-meshheading:18560600-T-Lymphocytes,
pubmed-meshheading:18560600-Thymus Gland
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pubmed:year |
2008
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pubmed:articleTitle |
Cytosolic sequestration of Prep1 influences early stages of T cell development.
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pubmed:affiliation |
Molecular Genetics Unit, San Raffaele Scientific Institute and Università Vita Salute San Raffaele, Milan, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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