18559663

Source:http://linkedlifedata.com/resource/pubmed/id/18559663

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0011155, umls-concept:C0030761, umls-concept:C0033105, umls-concept:C0239307, umls-concept:C0668289, umls-concept:C1835978
pubmed:issue	9
pubmed:dateCreated	2008-8-28
pubmed:abstractText	Melanocortin-4 receptor (MC4R) deficiency is the most frequent genetic cause of obesity. However, there is uncertainty regarding the degree of penetrance of this condition, and the putative impact of the environment on the development of obesity in MC4R mutation carriers is unknown.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/, http://linkedlifedata.com/resource/pubmed/grant/082390
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0372763
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/MC4R protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Melanocortin, Type 4
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	1939-327X
pubmed:author	pubmed-author:BalkauBeverleyB, pubmed-author:DinaChristianC, pubmed-author:FarooqiI SadafIS, pubmed-author:FroguelPhilippeP, pubmed-author:HorberFritzF, pubmed-author:JouretBéatriceB, pubmed-author:MeyreDavidD, pubmed-author:O'RahillyStephenS, pubmed-author:PotocznaNataschaN, pubmed-author:StutzmannFannyF, pubmed-author:TanKarenK, pubmed-author:TichetJeanJ, pubmed-author:VatinVincentV
pubmed:issnType	Electronic
pubmed:volume	57
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2511-8
pubmed:dateRevised	2010-9-14
pubmed:meshHeading	pubmed-meshheading:18559663-Adolescent, pubmed-meshheading:18559663-Adult, pubmed-meshheading:18559663-Age Distribution, pubmed-meshheading:18559663-Child, pubmed-meshheading:18559663-European Continental Ancestry Group, pubmed-meshheading:18559663-Feeding Behavior, pubmed-meshheading:18559663-Female, pubmed-meshheading:18559663-Humans, pubmed-meshheading:18559663-Hyperphagia, pubmed-meshheading:18559663-Male, pubmed-meshheading:18559663-Middle Aged, pubmed-meshheading:18559663-Mutation, pubmed-meshheading:18559663-Obesity, pubmed-meshheading:18559663-Pedigree, pubmed-meshheading:18559663-Penetrance, pubmed-meshheading:18559663-Phenotype, pubmed-meshheading:18559663-Prevalence, pubmed-meshheading:18559663-Receptor, Melanocortin, Type 4
pubmed:year	2008
pubmed:articleTitle	Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees.
pubmed:affiliation	Centre National de la Recherche Scientifique-8090, Institute of Biology, Pasteur Institute, Lille, France.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't