rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
12
|
pubmed:dateCreated |
2008-6-18
|
pubmed:abstractText |
Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an oncogenic factor stabilizing c-MYC protein and driving cellular transformation. We determine whether CIP2A expression can serve as marker for gastric cancer and investigate the mechanism underlying CIP2A-mediated transformation and cell proliferation.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1078-0432
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
14
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3722-8
|
pubmed:meshHeading |
pubmed-meshheading:18559589-Adult,
pubmed-meshheading:18559589-Aged,
pubmed-meshheading:18559589-Aged, 80 and over,
pubmed-meshheading:18559589-Autoantigens,
pubmed-meshheading:18559589-Cell Aging,
pubmed-meshheading:18559589-Cell Differentiation,
pubmed-meshheading:18559589-Cell Proliferation,
pubmed-meshheading:18559589-Female,
pubmed-meshheading:18559589-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18559589-HCT116 Cells,
pubmed-meshheading:18559589-HL-60 Cells,
pubmed-meshheading:18559589-HeLa Cells,
pubmed-meshheading:18559589-Humans,
pubmed-meshheading:18559589-Male,
pubmed-meshheading:18559589-Membrane Proteins,
pubmed-meshheading:18559589-Middle Aged,
pubmed-meshheading:18559589-RNA, Small Interfering,
pubmed-meshheading:18559589-Stomach Neoplasms,
pubmed-meshheading:18559589-Tumor Stem Cell Assay,
pubmed-meshheading:18559589-Up-Regulation
|
pubmed:year |
2008
|
pubmed:articleTitle |
CIP2A is overexpressed in gastric cancer and its depletion leads to impaired clonogenicity, senescence, or differentiation of tumor cells.
|
pubmed:affiliation |
Department of Microbiology/Key Laboratory for Experimental Teratology of Chinese Ministry of Education.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|