Linked Life Data

1855927

Source:http://linkedlifedata.com/resource/pubmed/id/1855927

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
105
pubmed:dateCreated
1991-8-29
pubmed:abstractText
We have measured the urinary excretion of nitrate, N-nitrosoproline, 3-methyladenine and 7-methylguanine in a human population at high risk for gastric cancer. A strong correlation was observed between nitrate and N-nitrosoproline excretion (p less than 0.00000); statistically significant correlations (p less than 0.05) were also observed for N-nitrosoproline with 3-methyladenine (p = 0.003) and with 7-methylguanine (p = 0.03) and for 7-methyl-guanine with nitrate (p = 0.02), although these correlations were sensitive to outliers. Smokers appeared to excrete slightly higher levels of 3-methyladenine than nonsmokers; no other difference was observed between smokers and nonsmokers or between drinkers and nondrinkers. The correlation between N-nitrosoproline excretion and nitrate excretion supports the hypothesis that elevated endogenous nitrate levels may contribute to elevated endogenous formation of N-nitroso compounds.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-5038
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
83-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Comparison of urinary nitrate, N-nitrosoproline, 7-methylguanine and 3-methyladenine levels in a human population at risk for gastric cancer.
pubmed:affiliation
Division of Toxicology, Massachusetts Institute of Technology, Cambridge.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.