Source:http://linkedlifedata.com/resource/pubmed/id/18559125
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-1-6
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pubmed:abstractText |
Diabetes mellitus (DM) is a known risk factor for pulmonary tuberculosis (PTB). This study aimed to determine if type 2 DM alters manifestations and treatment outcome of PTB. Records of 217 consecutive culture-proven PTB patients were analysed retrospectively. The manifestations and treatment outcomes of 74 patients with type 2 DM (PTB-DM group) were compared to 143 patients without DM (PTB group). PTB-DM patients showed higher frequencies of fever, haemoptysis, positive acid-fast bacilli sputum smears, and consolidation, cavity, and lower lung field lesions on chest radiographs, and higher mortality rate. Furthermore, type 2 DM, age 65 years, and extensive radiographic disease were factors independently associated with an unfavorable outcome. This study confirmed that clinical manifestations and chest radiographs of PTB patients associated with type 2 DM significantly depart from the typical presentation. Type 2 DM seems to have a negative effect on treatment outcome of PTB.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0950-2688
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
137
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
203-10
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pubmed:meshHeading |
pubmed-meshheading:18559125-Aged,
pubmed-meshheading:18559125-Antitubercular Agents,
pubmed-meshheading:18559125-Case-Control Studies,
pubmed-meshheading:18559125-Diabetes Mellitus, Type 2,
pubmed-meshheading:18559125-Female,
pubmed-meshheading:18559125-Humans,
pubmed-meshheading:18559125-Male,
pubmed-meshheading:18559125-Middle Aged,
pubmed-meshheading:18559125-Retrospective Studies,
pubmed-meshheading:18559125-Treatment Outcome,
pubmed-meshheading:18559125-Tuberculosis, Pulmonary
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pubmed:year |
2009
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pubmed:articleTitle |
Impact of type 2 diabetes on manifestations and treatment outcome of pulmonary tuberculosis.
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pubmed:affiliation |
Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
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pubmed:publicationType |
Journal Article
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