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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-8-26
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pubmed:abstractText |
The polymorphism of C1R was investigated in 570 unrelated Japanese individuals using isoelectric focusing and immunoblotting. A total of 11 different C1R phenotypes including a new pattern designated C1R 11-1 were observed. The allele frequencies were C1R*1 = 0.4561, C1R*2 = 0.3377, C1R*5 = 0.1956, C1R*8 = 0.0088 and C1R*R (C1R*9 and C1R*11) = 0.0018. The population data fitted the Hardy-Weinberg equilibrium. The C1R polymorphism in Japanese was shown to be controlled by 3 common alleles, C1R*1, C1R*2 and C1R*5, as compared to Caucasians where only the former 2 are present commonly. This complement system can be a useful genetic marker for anthropological studies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0001-5652
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
129-33
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1855783-Alleles,
pubmed-meshheading:1855783-Animals,
pubmed-meshheading:1855783-Complement C1r,
pubmed-meshheading:1855783-Continental Population Groups,
pubmed-meshheading:1855783-Female,
pubmed-meshheading:1855783-Gene Frequency,
pubmed-meshheading:1855783-Genetic Variation,
pubmed-meshheading:1855783-Humans,
pubmed-meshheading:1855783-Immunoblotting,
pubmed-meshheading:1855783-Isoelectric Focusing,
pubmed-meshheading:1855783-Japan,
pubmed-meshheading:1855783-Male,
pubmed-meshheading:1855783-Pedigree,
pubmed-meshheading:1855783-Phenotype,
pubmed-meshheading:1855783-Polymorphism, Genetic
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pubmed:year |
1991
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pubmed:articleTitle |
C1R subcomponent polymorphism in Japanese: description of a new allele.
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pubmed:affiliation |
Department of Legal Medicine, Yamanashi Medical University, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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