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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2008-8-11
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pubmed:abstractText |
The loss of myenteric neurons in the lower esophageal sphincter (LES) characterizes achalasia, an esophageal motor disorder. Because the presence of lymphocytic infiltrates suggests an immuno-mediated mechanism ongoing at the sites of disease, we investigated the T-cell receptor (TCR) repertoire and the ability to recognize human herpes virus type 1 (HSV-1) antigens of LES-infiltrating T lymphocytes in achalasia patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1572-0241
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pubmed:author |
pubmed-author:BaessoIleniaI,
pubmed-author:BaldanNicolaN,
pubmed-author:BertoAlessandroA,
pubmed-author:BrunPaolaP,
pubmed-author:CastagliuoloIgnazioI,
pubmed-author:CostantiniMarioM,
pubmed-author:FaccoMonicaM,
pubmed-author:PalùGiorgioG,
pubmed-author:RizzettoChristianC,
pubmed-author:SemenzatoGianpietroG,
pubmed-author:ZaninottoGiovanniG
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pubmed:issnType |
Electronic
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1598-609
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pubmed:meshHeading |
pubmed-meshheading:18557707-Adolescent,
pubmed-meshheading:18557707-Adult,
pubmed-meshheading:18557707-Aged,
pubmed-meshheading:18557707-Aged, 80 and over,
pubmed-meshheading:18557707-Antigens, Viral,
pubmed-meshheading:18557707-Cadaver,
pubmed-meshheading:18557707-Esophageal Achalasia,
pubmed-meshheading:18557707-Esophageal Sphincter, Lower,
pubmed-meshheading:18557707-Female,
pubmed-meshheading:18557707-Flow Cytometry,
pubmed-meshheading:18557707-Herpesvirus 1, Human,
pubmed-meshheading:18557707-Humans,
pubmed-meshheading:18557707-Male,
pubmed-meshheading:18557707-Middle Aged,
pubmed-meshheading:18557707-Myenteric Plexus,
pubmed-meshheading:18557707-Polymerase Chain Reaction,
pubmed-meshheading:18557707-Receptors, Antigen, T-Cell,
pubmed-meshheading:18557707-T-Lymphocytes
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pubmed:year |
2008
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pubmed:articleTitle |
T cells in the myenteric plexus of achalasia patients show a skewed TCR repertoire and react to HSV-1 antigens.
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pubmed:affiliation |
Department of Clinical and Experimental Medicine, Hematology and Clinical Immunology Branch, Padua University School of Medicine, Padova, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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