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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2008-8-21
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pubmed:abstractText |
Gene therapy for severe von Willebrand disease (vWD) seems an interesting treatment alternative with long-term therapeutic potential. We investigated the feasibility of targeting the liver for ectopic expression of physiologically active von Willebrand factor (vWF).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1524-4636
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1621-6
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18556568-Animals,
pubmed-meshheading:18556568-Bleeding Time,
pubmed-meshheading:18556568-Chlorides,
pubmed-meshheading:18556568-Cytomegalovirus,
pubmed-meshheading:18556568-Disease Models, Animal,
pubmed-meshheading:18556568-Factor VIII,
pubmed-meshheading:18556568-Feasibility Studies,
pubmed-meshheading:18556568-Ferric Compounds,
pubmed-meshheading:18556568-Gene Therapy,
pubmed-meshheading:18556568-Gene Transfer Techniques,
pubmed-meshheading:18556568-Humans,
pubmed-meshheading:18556568-Liver,
pubmed-meshheading:18556568-Mice,
pubmed-meshheading:18556568-Mice, Knockout,
pubmed-meshheading:18556568-Platelet Adhesiveness,
pubmed-meshheading:18556568-Platelet Aggregation,
pubmed-meshheading:18556568-Promoter Regions, Genetic,
pubmed-meshheading:18556568-Severity of Illness Index,
pubmed-meshheading:18556568-Thrombosis,
pubmed-meshheading:18556568-Time Factors,
pubmed-meshheading:18556568-alpha 1-Antitrypsin,
pubmed-meshheading:18556568-von Willebrand Diseases,
pubmed-meshheading:18556568-von Willebrand Factor
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pubmed:year |
2008
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pubmed:articleTitle |
Restoration of plasma von Willebrand factor deficiency is sufficient to correct thrombus formation after gene therapy for severe von Willebrand disease.
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pubmed:affiliation |
Laboratory for Thrombosis Research, K.U. Leuven Campus Kortrijk, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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